The research is part of the US National Institutes of Health’s Brain Research through Advancing Innovative Neurotechnologies Initiative - Cell Census Network (BICCN), a collaboration between hundreds of scientists. “These types of atlases really are laying the groundwork for a much better understanding of the human brain.” Researchers have previously mapped the human brain using techniques such as magnetic resonance imaging, but this is the first atlas of the whole human brain at the single-cell level, showing its intricate molecular interactions, adds Hannan. “It’s highly significant,” says Anthony Hannan, a neuroscientist at the Florey Institute of Neuroscience and Mental Health in Melbourne, Australia. The enormous cell atlas offers a detailed snapshot of the most complex known organ. The work, published in a package of 21 papers today in Science, Science Advances and Science Translational Medicine, will aid the study of diseases, cognition and what makes us human, among other things, say the authors. Researchers have created the largest atlas of human brain cells so far, revealing more than 3,000 cell types - many of which are new to science. Credit: Dennis Kunkel Microscopy/Science Photo Library Insights into thousands of types of brain cell could improve understanding of diseases and cognition.
